Achromobacter xylosoxidans respiratory tract infection in cystic fibrosis patients

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Clinical impact of Achromobacter xylosoxidans colonization/infection in patients with cystic fibrosis

The rate of diagnosis of colonization/infection of the airways with Achromobacter xylosoxidans has increased in cystic fibrosis patients, but its clinical significance is still controversial. This retrospective, case-control study aimed to evaluate the clinical impact of A. xylosoxidans colonization/infection in cystic fibrosis patients. Individuals who were chronically colonized/infected (n=10...

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A (formerly Alcaligenes) xylosoxidans is a newly emerging microorganism isolated with increased frequency from the lungs of patients with cystic fibrosis (CF), but information about its clinical relevance is limited (1). A. xylosoxidans is innately resistant to many antimicrobial drugs (2), except piperacillin, piperacillintazobactam, and imipenem, and moderately susceptible to ceftazidime (45%...

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Achromobacter xylosoxidans infection in cystic fibrosis siblings with different outcomes: Case reports

INTRODUCTION The clinical relevance of Achromobacter xylosoxidans infection in cystic fibrosis (CF) remains controversial. This emerging agent in CF has been associated with increased lung inflammation, more frequent exacerbations and more severe lung disease. We describe a pair of CF siblings chronically colonized by the same multilocus genotype of A. xylosoxidans with different clinical cours...

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ژورنال

عنوان ژورنال: European Journal of Clinical Microbiology & Infectious Diseases

سال: 2011

ISSN: 0934-9723,1435-4373

DOI: 10.1007/s10096-011-1182-5